Cancer chemoprevention – selected molecular mechanisms
نویسندگان
چکیده
منابع مشابه
Cancer Chemoprevention and Piperine: Molecular Mechanisms and Therapeutic Opportunities
Cancer is a genetic disease characterized by unregulated growth and dissemination of malignantly transformed neoplastic cells. The process of cancer development goes through several stages of biochemical and genetic alterations in a target cell. Several dietary alkaloids have been found to inhibit the molecular events and signaling pathways associated with various stages of cancer development a...
متن کاملMolecular mechanisms of chemoprevention and therapy of cancer by retinoids.
Chemoprevention is the use of noncytotoxic therapeutic intervention at the early stages of carcinogenesis against the development and progression of mutant clones to invasive cancer. Retinoids are the most extensively studied and one of the most prominent groups of chemopreventive agents to reach clinical trials. Acute promyelocytic leukemia is the first human malignancy that is successfully tr...
متن کاملMechanisms underlying chemoprevention of ovarian cancer.
Ovarian cancer remains the most lethal of the gynecological cancers. Although relatively uncommon, afflicting 1 of 70 women in the United States, the high mortality rate makes this disease a major health concern. The high mortality rate arises from the lack of an effective screening approach combined with inadequate therapeutic approaches for advanced disease. Indeed, fewer than 25% of ovarian ...
متن کاملMolecular mechanisms involved in multidrug resistance in breast cancer therapy
Breast cancer is the most prevalent cancer in women. Chemotherapy is the main strategy in the treatment of this disease especially in the advanced form of the disease. Despite the recent progress in the development of new chemotherapy, the effectiveness of these drugs has dramatically reduced due to multidrug resistance. The phenotype of multidrug resistance (MDR) can occur through different me...
متن کاملChemoprevention by resveratrol: molecular mechanisms and therapeutic potential.
Resveratrol, a polyphenol found in numerous plant species, including mulberries, peanuts and grapes, has shown to possess chemopreventive properties against several cancers, and cardiovascular diseases. Recently, resveratrol has been shown to have positive effects on age longevity, lipid levels and a preventative quality against certain cancers and viral infections. Resveratrol induces apoptosi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2017
ISSN: 0032-5449,1732-2693
DOI: 10.5604/01.3001.0010.3799